Medical professionals providing compassionate cancer care
Columbia, South Carolina

Fight cancer with
compassion and
cutting-edge care

Advanced oncology treatments, personalized to you — right here in Columbia. Our team of specialists combines the latest science with genuine human connection, so you face every step with confidence and support.

Trusted by thousands of patients across the Midlands

Comprehensive cancer care,
under one roof

From diagnosis through survivorship, we provide the full spectrum of oncology services — so you don't have to navigate this alone.

Medical Oncology

Personalized chemotherapy, immunotherapy, and targeted therapy plans designed around your specific diagnosis and health profile.

Radiation Oncology

Precision radiation therapy using advanced technology to target tumors while protecting the healthy tissue around them.

Hematology

Diagnosis and treatment of blood disorders, including blood cancers like leukemia, lymphoma, and myeloma.

Supportive & Palliative Care

Managing side effects, pain, and emotional distress — so you can focus on what matters most: living well.

Cancer Screening & Prevention

Early detection saves lives. We offer evidence-based screening programs and risk assessment for all types of cancer.

Survivorship Programs

Ongoing monitoring, wellness planning, and follow-up care after treatment ends — because your journey doesn't stop here.

Modern cancer treatment facility in Columbia SC

A center built around
you — not just your diagnosis

At Palmetto Health Cancer Center, we believe that fighting cancer shouldn't mean facing it alone. Located in the heart of Columbia at 5 Richland Medical Park Drive, our center brings together world-class oncologists, nurses, nutritionists, and support specialists who treat the whole person — not just the disease.

25+ Years Serving
Columbia
50+ Dedicated
Specialists
10,000+ Patients Treated
Annually

We invest in the latest technology — from advanced radiation systems to personalized treatment protocols — so every patient in the Midlands has access to the same standard of care found at the nation's top cancer centers.

Four pillars that guide
every decision we make

Your care plan is as unique as you are. Here's how we make sure it's built the right way — every time.

01

Personalized Treatment

Every cancer is different. We tailor chemotherapy, radiation, and surgical options to your specific condition, genetics, and goals.

02

Coordinated Care

Multiple specialists working in sync — so you get one clear plan, not conflicting opinions or endless referrals.

03

Emotional Support

Counseling, support groups, and social work services are woven into your care — because mental health is health.

04

Family Involvement

Your loved ones are part of the team. We welcome them into consultations, education sessions, and care planning.

Healthcare team collaborating on patient care

Hear from those who
walked this path with us

"When I was first diagnosed, I felt completely lost. The team at Palmetto Health didn't just treat my cancer — they treated me. They explained everything, included my family, and never made me feel like just another chart."

Patient Breast Cancer Survivor

"The radiation oncologists here are exceptional. They took the time to walk me through every step of my treatment, answered every question, and made what could have been terrifying feel manageable."

Patient Lung Cancer Patient

"As a caregiver, I was overwhelmed. The social workers and nurses here held my hand through it all — from insurance paperwork to emotional support. This center truly cares about the whole family, not just the patient."

Patient Family Member Caregiver
Medical team providing patient care

You don't have to face this alone.
Let's start your journey today.

Whether you need a referral, a second opinion, or simply want to learn more about our services — we're here. Call us or send a message, and a member of our team will reach out within one business day.

Call (803) 434-3600

We're here when you need us

Our doors are open to patients, families, and referring physicians. Reach out by phone, email, or visit us in person — we'll welcome you with kindness and respect.

Address 5 Richland Medical Park Dr
Columbia, SC 29203
Hours Monday – Friday: 8:00 AM – 5:00 PM
Saturday – Sunday: Closed

Send Us a Message

A member of our team will respond within one business day.

Thank you! We've received your message and will be in touch soon.
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